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簡要描述:寬場NV顯微鏡是一款基于氮-空位(Nitrogen-Vacancy, NV)色心光探測磁共振(Optically Detected Magnetic Resonance, ODMR)原理的寬場磁顯微鏡,具有空間分辨率高、視野范圍大、可探測磁場動態(tài)范圍大、成像速度快等特點。
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寬場NV顯微鏡WNVM
Widefield NV microscope
寬場NV顯微鏡WNVM是一款基于氮-空位(Nitrogen-Vacancy, NV)色心光探測磁共振(Optically Detected Magnetic Resonance, ODMR)原理的寬場磁顯微鏡,具有空間分辨率高、視野范圍大、可探測磁場動態(tài)范圍大、成像速度快等特點。
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應(yīng)用領(lǐng)域
隕石剩余磁化的磁場成像和光學(xué)成像
地質(zhì)樣本中的剩余磁化強度記錄了過去行星磁場的強度和方向。傳統(tǒng)上,這種磁化是通過測量尺寸在毫米到厘米的樣品凈磁矩進行分析。然而地質(zhì)樣品通常在亞毫米尺寸上具有結(jié)構(gòu)和物質(zhì)的不均勻性,只有小部分鐵磁顆粒具有剩余磁化強度,因此需要高空間分辨率、高磁矩靈敏度的成像技術(shù)。
寬場NV顯微鏡通過減少金剛石與樣品之間的距離, 能夠?qū)崿F(xiàn)磁矩靈敏度10-16 A·m2的探測,能夠應(yīng)用于地質(zhì)、磁隕石的探測分析中。
參考文獻:Geochem. Geophys. Geosyst. 18, 3254 (2017)
肺癌組織熒光成像和磁場成像
傳統(tǒng)磁共振成像受限于低靈敏度和低空間分辨率,很難應(yīng)用于組織水平微米分辨率的成像。寬場NV顯微鏡結(jié)合量子精密測量與免疫磁標記技術(shù),能夠?qū)崿F(xiàn)高分辨率的腫瘤組織磁成像,可用于肺癌等檢測。
寬場NV顯微鏡在生物組織成像上具絕對磁定量、避免背景信號的干擾、磁信號的高穩(wěn)定性、兼具磁和光多模態(tài)成像等優(yōu)勢。
參考文獻:PNAS 119, e2118876119 (2022)
測試案例
Global Developer & Manufacturer Of High-Precision Scientific Instruments
CIQTEK's high-precision instruments help scientists explore materials and physical properties at the microscopic level.
ClQTEK meets the needs of its customers by providing customized products and complete application solutions in the areas of environmental science, biochemistry, chip semiconductors, and materials science, enabling customers to innovate and increase productivity.
The main business includes Scanning Electron Microscopes (SEMs), Electron Paramagnetic Resonance (Electron Spin Resonance) Spectroscopy, Scanning NV Probe Microscopes, and BET Surface Area & Pore Analyzers.
CIQTEK currently has over 700 employees, including 70% of the R&D team. A total of 12 application centers provide customers with sample testing, experimental comparison, performance evaluation, application direction development, and advanced training on product operation.
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